Signature Performance Appoints David Isaacks as CEO as Part of Planned Leadership Evolution

Signature Performance, a healthcare technology and administrative services company focused on reducing administrative costs, complexity, and friction across payer and provider operations, announced a planned leadership evolution today designed to strengthen enterprise execution and support the company’s next phase of growth. As part of this evolution, David Isaacks has been appointed Chief Executive Officer (CEO), bringing deep enterprise healthcare leadership.  Founder and Chief Executive Officer Allen Fredrickson will transition to the role of Founder and Executive Chairman, and Karen Hudgins, President and former Chief Operating Officer, will move into a new role as Executive Advisor to the Chairman, reinforcing continuity, governance clarity, and long-term strategic focus as the organization evolves.

As Founder and Executive Chairman, Fredrickson will remain actively engaged in long‑term direction, key relationships, industry thought leadership, and strengthening the culture that supports sustained performance. Hudgins will focus on long‑term strategic initiatives and upcoming acquisition opportunities in 2026, helping position Signature for future growth while preserving institutional knowledge and reinforcing clear governance as the organization evolves.

Strengthening Administrative Performance Amid Rising Complexity

Healthcare leaders are being asked to do more with less, while administrative complexity continues to rise. Costs and staffing pressure, compliance expectations, and service demands are converging at the same time. Signature exists to improve the administrative experience in healthcare by reducing burden, improving accuracy, and elevating the end-to-end experience for the people who do the work and the people affected by it. This leadership evolution is designed to strengthen that value by increasing continuity, sharpening accountability, and accelerating the company’s ability to deliver consistent outcomes at scale.

A Client-first Model Built for Outcomes, Not Dependency

Signature is purpose-built to help clients improve performance without surrendering control. Its operating model emphasizes transparency, measurable results, and long-term capability building. Signature partners with clients to stabilize day-to-day execution, prove improvement through clear performance measures, and strengthen the systems and routines that allow progress to sustain. The goal is not simply to take work off a client’s plate, but to reduce friction, increase reliability, and leave the client stronger.

Integrated Technology, Advisory, and MSO Capabilities

Signature delivers this value through an integrated platform that combines technology, advisory services, and MSO (managed services organization) capabilities into one coordinated approach. Technology-enabled workflow, analytics, and performance management are paired with operational execution and advisory depth to reduce rework, improve first-pass accuracy, strengthen throughput stability, and elevate service experience across both claims administration and revenue cycle.

“Externally, the only lens that matters is what this means for our clients and partners,” said Allen Fredrickson, Founder and Executive Chairman of Signature Performance. “Our mission and vision are unchanged. We are doubling down on the things that create uncommon value: technology-enabled capabilities, advisory depth, operational execution, and exceptional talent. This evolution positions Signature to be an even more comprehensive, trusted partner with greater consistency and capability for our clients.”

David Isaacks Brings Enterprise Healthcare Leadership Across the Ecosystem

Isaacks joined Signature in October 2025 after a distinguished 20-year healthcare leadership career spanning complex systems and diverse care environments. His experience includes leadership roles within the U.S. Department of Veterans Affairs, as well as academic medicine and research medicine. He is a Fellow of the American College of Healthcare Executives (FACHE) and previously served as an ACHE Regent.

Most recently, Isaacks served as Regional Chief Executive Officer (Network Director) for the VA Sunshine Healthcare Network, leading a $10.7 billion enterprise of 36,000+ employees serving 1.5 million Veterans across Florida, southern Georgia, Puerto Rico, and the U.S. Virgin Islands. Under his leadership, the network achieved historic results, including being named the number one Best Place to Work in VA for two consecutive years and earning the network’s first-ever CMS 5-Star hospital rating.

As CEO, Isaacks will lead enterprise execution and performance across Signature’s technology, advisory, and MSO capabilities supporting claims administration and revenue cycle outcomes, reinforcing a single point of accountability for operating performance and client results.

“Clients are looking for partners who deliver outcomes with consistency, transparency, and integrity,” said David Isaacks, Chief Executive Officer, Signature Performance. “My focus is to expand what clients can count on from Signature: less administrative friction, higher accuracy, faster and more stable cycles, and a better experience for the people carrying the work every day.”

About Signature Performance

Founded in 2004, Signature Performance is a healthcare technology and administrative services company that helps payer and provider organizations reduce administrative cost and complexity. The company delivers integrated technology, advisory, and managed services capabilities across federal and commercial healthcare to improve accuracy, efficiency, and operational performance.